Aplastic Anemia with Ethosuximide

Aplastic anemia.

PURPOSE OF REVIEW Most acquired aplastic anemia is the result of immune-mediated destruction of hematopoietic stem cells causing pancytopenia and an empty bone marrow, which can be successfully treated with either immunosuppressive therapy or hematopoietic stem-cell transplantation. RECENT FINDINGS In aplastic anemia, oligoclonally expanded cytotoxic T cells induce apoptosis of hematopoietic ...

Aplastic anemia with platelet thrombi.

7’. K., a 67 year old white female, was admitted to the Albert Einstein Medical Center, Southern Division, on September 6, 1949, with the chief complaint of fever and soremness of the sisouthi and gums. She was ap )areIit1y well until two weeks before admissioni when she developed a cough, sore throat amid a mild coryza. Shse was treated at home with aspirin, phemsacetins, co(leimse, caffeine, ...

Aplastic anemia associated with pregnancy.

Aplastic anemia is not an uncommon disorder. Estimated frequency is 3-6 per million populations per year. Occurrence of aplastic anemia however, concurrently with pregnancy in a previously healthy woman is a rare phenomenon. Since 1888 when it was first described not more than a handful of cases have been reported in literature. Pregnancy associated with marrow aplasia poses great problems for ...

ALLOGENIC BONE MARROW TRANSPLANTATION IN APLASTIC ANEMIA

Eighteen patients, twelve men and six women, with aplastic anemia underwent allogenic bone marrow transplantation (BMT) from HLA-matched siblings during the period of 1990 to 1996. The conditioning regimen was cyclophosphamide with or without busulfan, depending on the cause of aplasia. Antilymphocyte globulin (ALG) and cyclosporine were used for rejection and acute GVHD prophylaxis, respe...

Aplastic Anemia - Diagnos tics and Therapy of Acquired Aplastic Anemia